Affiliation:
1. Institute of Hygiene, University of Cologne, Cologne, Germany
Abstract
When 2,3- or 3,4-dihydroxybenzoic acid, 3,4-dihydroxyphenylalanine, and 3,4-dihydroxycinnamic acid are added to growth media, they are converted to a characteristic brown pigment by
Cryptococcus neoformans.
This pigment formation has hitherto been encountered only when this microorganism was cultivated on media containing
Guizotia abyssinica
seed. This phenomenon can be used for differentiating
Cryptococcus neoformans
from
Candida albicans.
Possible precursors of these
o
-diphenols (quinic acid, aromatic monohydroxy acids, or tyrosine) do not give rise to the brown pigmentation.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
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