Stimulation of expression of the human endogenous retrovirus genome by female steroid hormones in human breast cancer cell line T47D-Reference-Cited by-同舟云学术

Stimulation of expression of the human endogenous retrovirus genome by female steroid hormones in human breast cancer cell line T47D

Published:1987-06 Issue:6 Volume:61 Page:2059-2062
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Ono M,Kawakami M,Ushikubo H

Abstract

Expression of the human endogenous retrovirus genome HERV-K, homologous to mouse mammary tumor virus, was investigated in cultured human tumor cells. In several cell lines, the HERV-K genome was expressed as an 8.8-kilobase poly(A)+ RNA which appeared to be a full-size transcript of this genome. In the human breast cancer cell line T47D, stimulation of HERV-K genome expression by progesterone was observed after estradiol treatment.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.61.6.2059-2062.1987

Reference23 articles.

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