Burkholderia from Fungus Gardens of Fungus-Growing Ants Produces Antifungals That Inhibit the Specialized Parasite Escovopsis

Author:

Francoeur Charlotte B.12ORCID,May Daniel S.1ORCID,Thairu Margaret W.1ORCID,Hoang Don Q.12ORCID,Panthofer Olivia1,Bugni Tim S.3ORCID,Pupo Mônica T.4ORCID,Clardy Jon5ORCID,Pinto-Tomás Adrián A.678ORCID,Currie Cameron R.12ORCID

Affiliation:

1. Department of Bacteriology, University of Wisconsin—Madison, Madison, Wisconsin, USA

2. Department of Energy Great Lakes Bioenergy Research Center, University of Wisconsin—Madison, Madison, Wisconsin, USA

3. Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin—Madison, Madison, Wisconsin, USA

4. Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil

5. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA

6. Centro de Investigación en Estructuras Microscópicas, Universidad de Costa Rica, San José, Costa Rica

7. Departamento de Bioquímica, Facultad de Medicina, Universidad de Costa Rica, San José, Costa Rica

8. Centro de Investigación en Biología Celular y Molecular, Universidad de Costa Rica, San José, Costa Rica

Abstract

Many organisms partner with microbes to defend themselves against parasites and pathogens. Fungus-growing ants must protect Leucoagaricus spp., the fungal mutualist that provides sustenance for the ants, from a specialized fungal parasite, Escovopsis spp.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | National Institutes of Health

National Science Foundation

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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