Immunobiology of the Classical Lancefield Group A Streptococcal Carbohydrate Antigen-Reference-Cited by-同舟云学术

Immunobiology of the Classical Lancefield Group A Streptococcal Carbohydrate Antigen

Published:2021-11-16 Issue:12 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Gao Nina J.¹²,Rodas Lima Ervin²,Nizet Victor¹²³^ORCID

Affiliation:

1. Biomedical Sciences Graduate Program, UC San Diego, La Jolla, California, USA

2. Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, UC San Diego, La Jolla, California, USA

3. Skaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, La Jolla, California, USA

Abstract

Group A Streptococcus (GAS) is a preeminent human bacterial pathogen causing hundreds of millions of infections each year worldwide. In the clinical setting, the bacterium is easily identified by a rapid antigen test against the group A carbohydrate (GAC), a polysaccharide that comprises 30 to 50% of the GAS cell wall by weight.

Funder

CARB-X

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00292-21

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