Permeability and Susceptibility of Escherichia coli to β- Lactam Compounds

Author:

Clark David1

Affiliation:

1. Department of Microbiology, University of Illinois, Urbana, Illinois 61801

Abstract

In general, the susceptibility of envelope mutants of Escherichia coli to β-lactam compounds correlates well with the permeability of these antibiotics through the outer membrane. However, several mutants were isolated which, although apparently freely permeable to penicillins, showed only marginal increases in susceptibility to these agents.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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