p17-Modulated Hsp90/Cdc37 Complex Governs Oncolytic Avian Reovirus Replication by Chaperoning p17, Which Promotes Viral Protein Synthesis and Accumulation of Viral Proteins σC and σA in Viral Factories-Reference-Cited by-同舟云学术

p17-Modulated Hsp90/Cdc37 Complex Governs Oncolytic Avian Reovirus Replication by Chaperoning p17, Which Promotes Viral Protein Synthesis and Accumulation of Viral Proteins σC and σA in Viral Factories

Published:2022-03-23 Issue:6 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Huang Wei‐Ru¹²,Li Jyun-Yi¹²,Wu Yi-Ying¹²,Liao Tsai-Ling³⁴⁵,Nielsen Brent L.⁶,Liu Hung-Jen¹²⁴⁵⁷^ORCID

Affiliation:

1. Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan

2. The iEGG and Animal Biotechnology Center, National Chung Hsing University, Taichung, Taiwan

3. Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan

4. Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan

5. Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung, Taiwan

6. Department of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, USA

7. Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan

Abstract

Molecular mechanisms that control stabilization of ARV proteins and the intermolecular interactions among inclusion components remain largely unknown. Here, we show that the ARV p17 is an Hsp90 client protein.

Funder

Ministry of Education

Ministry of Science and Technology, Taiwan

National Chung-Hsing University

Taichung Veterans General Hospital

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00074-22

Reference63 articles.