Affiliation:
1. Division of Allergy, Immunology and Infectious Diseases, The Children's Hospital of Philadelphia, Pennsylvania 19104, USA. gesser@email.chop.edu
Abstract
Using in situ hybridization, we demonstrated that latent herpes simplex virus type 1 (HSV-1) gene expression is prevalent in human adult nodose ganglia. This suggests that infection of gastrointestinal sensory nerves, probably through swallowed virus-laden oral secretions, occurs commonly and that HSV-1 reactivating from this site may play a role in recurrent gastrointestinal disorders.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
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