Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses-Reference-Cited by-同舟云学术

Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses

Published:2018-08 Issue:8 Volume:62 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Yoon Jeong-Joong¹,Toots Mart¹,Lee Sujin²³,Lee Myung-Eun¹,Ludeke Barbara⁴,Luczo Jasmina M.⁵,Ganti Ketaki⁶,Cox Robert M.¹,Sticher Zachary M.⁷,Edpuganti Vindya⁷,Mitchell Deborah G.⁷,Lockwood Mark A.⁷,Kolykhalov Alexander A.⁷,Greninger Alexander L.⁸,Moore Martin L.²³,Painter George R.⁷,Lowen Anice C.⁶^ORCID,Tompkins Stephen M.⁵^ORCID,Fearns Rachel⁴,Natchus Michael G.⁷,Plemper Richard K.¹

Affiliation:

1. Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA

2. Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA

3. Children's Healthcare of Atlanta, Atlanta, Georgia, USA

4. Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA

5. Center for Vaccines and Immunology, University of Georgia, Athens, Georgia, USA

6. Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA

7. Emory Institute for Drug Development, Emory University, Atlanta, Georgia, USA

8. Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA

Abstract

Morbidity and mortality resulting from influenza-like disease are a threat, especially for older adults. To improve case management, next-generation broad-spectrum antiviral therapeutics that are efficacious against major drivers of influenza-like disease, including influenza viruses and respiratory syncytial virus (RSV), are urgently needed.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

DOD | Defense Threat Reduction Agency

HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00766-18

Reference80 articles.

1. Hospitalizations Associated With Influenza and Respiratory Syncytial Virus in the United States, 1993–2008