Affiliation:
1. LSG & Associates, Santa Monica, California, USA
Abstract
ABSTRACT
Dientamoeba fragilis
is a single-celled protozoan, closely related to the trichomonads. Reported worldwide as causing human gastrointestinal symptoms,
D. fragilis
is very common and is second only to
Blastocystis
spp. Dientamoebiasis equals or exceeds the incidence of giardiasis. This minireview includes diagnostic options, clinical relevance, therapy, an animal model, the confirmed cyst stage, and sequencing data. The development of a rodent model, fulfilling Koch's postulates, and the confirmation of a cyst stage have clarified transmission routes, including fecal-oral transmission. The prevalence of
D. fragilis
varies between 0% to over 82%; results depend on the geographic location, group studied, and diagnostic methods used.
Publisher
American Society for Microbiology
Cited by
62 articles.
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