Evaluation of the Efficacy of Doxycycline, Ciprofloxacin, Levofloxacin, and Co-trimoxazole Using In Vitro and In Vivo Models of Q Fever-Reference-Cited by-同舟云学术

Evaluation of the Efficacy of Doxycycline, Ciprofloxacin, Levofloxacin, and Co-trimoxazole Using In Vitro and In Vivo Models of Q Fever

Published:2021-10-18 Issue:11 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Clay K. A.¹²,Hartley M. G.²^ORCID,Armstrong S.²,Bewley K. R.³^ORCID,Godwin K.³,Rayner E.³,Vipond J.³,Bailey M.¹,Atkins T. P.²⁴,Norville I. H.²

Affiliation:

1. Academic Department, Royal Centre for Defence Medicine (Academia and Research), Birmingham, United Kingdom

2. CBR Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom

3. Public Health England, Porton Down, Salisbury, Wiltshire, United Kingdom

4. College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom

Abstract

Q fever, caused by the intracellular pathogen Coxiella burnetii , is traditionally treated using tetracycline antibiotics, such as doxycycline. Doxycycline is often poorly tolerated, and antibiotic-resistant strains have been isolated.

Funder

MOD | Defence Science and Technology Laboratory

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00673-21

Reference47 articles.

1. Relation between Q fever notifications and Coxiella burnetii infections during the 2009 outbreak in the Netherlands

2. One-year follow-up of patients of the ongoing Dutch Q fever outbreak: clinical, serological and echocardiographic findings

3. Chronic Q Fever in the Netherlands 5 Years after the Start of the Q Fever Epidemic: Results from the Dutch Chronic Q Fever Database

4. Q fever

5. Epidemiological features of Coxiella burnetii infection in England and Wales: 1984 to 1994;Pebody RG;Commun Dis Rep CDR Rev,1996

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Prevalence of extended spectrum beta-lactamase (ESBL) Escherichia coli recovered from ICU and non-ICU at dr. Zainoel Abidin General Hospital;BIO Web of Conferences;2024

2. Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis;PLOS Pathogens;2023-07-03

3. Evaluation of Alternative Doxycycline Antibiotic Regimes in an Inhalational Murine Model of Q Fever;Antibiotics;2023-05-16

4. The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response;Cell Reports;2022-12

5. Antibiotic persistence of intracellular Brucella abortus;PLOS Neglected Tropical Diseases;2022-07-26