Virion-Associated RNA Primer for Rous Sarcoma Virus DNA Synthesis: Isolation from Uninfected Cells

Author:

Sawyer Robert C.1,Harada Fumio1,Dahlberg James E.1

Affiliation:

1. Department of Physiological Chemistry, University of Wisconsin Medical School, Madison, Wisconsin 53706

Abstract

Uninfected chicken, duck, rat, and human fibroblast cells in culture contained a tRNA-like RNA molecule which was structurally identical to a virion-associated RNA primer for in vitro Rous sarcoma virus DNA synthesis. This primer RNA appeared to be a normal tRNA of these cells. It was not found in a number of lower eukaryotic cells or in Escherichia coli.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference31 articles.

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3. The low molecular weight RNA's of Rous sarcoma virus. I. The 4S RNA;Bishop J. M.;Virology,1970

4. Bishop J. M. C. Tsan-Deng A. J. Faras H. M. Goodman W. E. Levinson J. M. Taylor and H. E. Varmus. 197:3. Transcription of the Rous sarcoma virus genome by RNA-directed DNA polymerase p. 15-31. In C. F. Fox (ed.) Virus research. Academic Press Inc. New York.

5. Ribonucleic acid components of BAI strain A (mveloblastosis) avian tumor virus;Bonar R. A.;Cancer Res.,1967

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