Screening the Pathogen Box for Molecules Active against Plasmodium Sexual Stages Using a New Nanoluciferase-Based Transgenic Line of P. berghei Identifies Transmission-Blocking Compounds-Reference-Cited by-同舟云学术

Screening the Pathogen Box for Molecules Active against Plasmodium Sexual Stages Using a New Nanoluciferase-Based Transgenic Line of P. berghei Identifies Transmission-Blocking Compounds

Published:2018-11 Issue:11 Volume:62 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Calit Juliana¹,Dobrescu Irina¹,Gaitán Xiomara A.¹,Borges Miriam H.¹,Ramos Marisé S.¹,Eastman Richard T.²,Bargieri Daniel Y.¹

Affiliation:

1. Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

2. Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, USA

Abstract

Malaria remains an important parasitic disease with a large morbidity and mortality burden. Plasmodium transmission-blocking (TB) compounds are essential for achieving malaria elimination efforts.

Funder

Instituto Serrapilheira

HHS | NIH | National Center for Advancing Translational Sciences

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

MCTI | Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01053-18