Identification of a Novel Interferon Lambda Splice Variant in Chickens-Reference-Cited by-同舟云学术

Identification of a Novel Interferon Lambda Splice Variant in Chickens

Published:2023-03-30 Issue:3 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Chen Jing¹²,Li Peiheng²,Zou Wancheng²,Jiang Yuhang²,Li Letian²,Hao Pengfei²,Gao Zihan²,Qu Qiaoqiao²,Pang Zhaoxia²,Zhuang Xinyu²,Nan Fulong²^ORCID,Jin Ningyi¹²,Du Shouwen²,Li Chang²^ORCID

Affiliation:

1. College of Veterinary Medicine, Key Lab for Zoonoses Research, Ministry of Education, Jilin University, Changchun, China

2. Research Unit of Key Technologies for Prevention and Control of Virus Zoonoses, Chinese Academy of Medical Sciences, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China

Abstract

Interferons (IFNs) are critical soluble factors in the immune system, and are composed of 3 types (I, II, and III) that utilize different receptor complexes (IFN-αR1/IFN-αR2, IFN-γR1/IFN-γR2, and IFN-λR1/IL-10R2, respectively). Herein, we identified IFNL from the genomic sequences of chicken and termed it chIFNL3a, located on chromosome 7 of chicken.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01743-22

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4. Characterization and transcriptional analysis of the mouse Chromosome 16 cytokine receptor gene cluster

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