Exploring Host-Binding Machineries of Mycobacteriophages with AlphaFold2-Reference-Cited by-同舟云学术

Exploring Host-Binding Machineries of Mycobacteriophages with AlphaFold2

Published:2023-03-30 Issue:3 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Cambillau Christian¹²^ORCID,Goulet Adeline³^ORCID

Affiliation:

1. School of Microbiology, University College Cork, Cork, Ireland

2. AlphaGraphix, Formiguères, France

3. Laboratoire d’Ingénierie des Systèmes Macromoléculaires, Institut de Microbiologie, Bioénergies et Biotechnologie, CNRS and Aix-Marseille Université, Marseille, France

Abstract

Mycobacteria include both saprophytes, such as the model system Mycobacterium smegmatis , and pathogens, such as Mycobacterium tuberculosis and Mycobacterium abscessus , that are poorly responsive to antibiotic treatments and pose a global public health problem. Mycobacteriophages have been collected at a very large scale over the last decade, and they have proven to be valuable tools for mycobacteria genetic manipulation, rapid diagnostics, and infection treatment.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01793-22

Reference76 articles.

1. Comparative Phylogenomics of Pathogenic and Non-Pathogenic Mycobacterium

2. Taxonomy, Physiology, and Natural Products of Actinobacteria

3. Alternatives to Antibiotics against Mycobacterium abscessus

4. Unraveling the Structure of the Mycobacterial Envelope

5. The thick waxy coat of mycobacteria, a protective layer against antibiotics and the host's immune system

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