Production of Nivalenol and Fusarenone-X by Fusarium tricinctum Fn-2B on a Rice Substrate

Author:

Lee Yin-Won1,Mirocha C. J.1

Affiliation:

1. Department of Plant Pathology, University of Minnesota, St. Paul, Minnesota 55108

Abstract

Fusarium tricinctum Fn-2B was grown on a rice substrate at room temperature (22 to 26°C) for 2 weeks followed by growth at a low temperature (10 to 12°C) for an additional 2 weeks. A total of 1.5 g of nivalenol and 80 mg of fusarenone-X were obtained from 2 kg of rice culture. The methods of production, extraction, and purification are described.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference7 articles.

1. Bottalico A. P. Lerario and A. Visconti. 1983. Mycotoxins occurring in Fusarium-infected maize ears in the field in some European countries p. 375-382. Proceedings of the Internation Symposium on Mycotoxins. Mycotoxin Symposium National Research Center Cairo Egypt.

2. Studies on the toxic substances in barley infected with Fusarium spp;Morooka N.;Jpn. J. Food Hyg.,1972

3. Nivalenol, a toxic principle of Fusarium nivale;Tatsuno T.;Chem. Pharm. Bull.,1968

4. Environmental factors influencing the production of fusarenone-X, a cytotoxic mycotoxin of Fusarium nivale Fn-2B;Ueno T.;Chem. Pharm. Bull.,1970

5. Toxicological approaches to the metabolites of Fusaria. II. Isolation of fusarenone-X from the culture filtrate of Fusarium nivale Fn-2B;Ueno Y.;Jpn. J. Exp. Med.,1977

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