Characterization of the defect in the Escherichia coli mutT1 mutator gene-Reference-Cited by-同舟云学术

Characterization of the defect in the Escherichia coli mutT1 mutator gene

Published:1990-05 Issue:5 Volume:172 Page:2802-2803
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Bhatnagar S K¹,Bullions L C¹,Lew G¹,Bessman M J¹

Affiliation:

1. McCollum-Pratt Institute, Johns Hopkins University, Baltimore, Maryland 21218.

Abstract

With a probe constructed from the wild-type gene, a DNA fragment containing the entire mutT1 mutator gene was isolated and cloned into pUC18. Nucleotide sequence analysis revealed that the mutator defect was most likely due to an IS1 insertion into the wild-type gene.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.172.5.2802-2803.1990

Reference15 articles.

1. Molecular cloning and nucleotide sequence of the mutT mutator of Escherichia coli that caused A:T to C:G transversion;Akiyama M.;Mol. Gen. Genet.,1987

2. A specific role of mutT protein: to prevent dG * dA mispairing in DNA replication;Akiyama M.;Proc. Natl. Acad. Sci. USA,1989

3. Screening Xgt recombinant clones by hybridization to single plaques in situ;Benton W. D.;Science,1977

4. Studies on the mutator gene, mutT of Escherichia coli;Bhatnagar S. K.;J. Biol. Chem.,1988

5. IS1 insertion generates duplication of a nine base pair sequence at its target site;Grindley N. D. F.;Cell,1978

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