Affiliation:
1. Unidad de Genética Molecular, Hospital Ramón y Cajal, Madrid, Spain.
Abstract
Microcin C7 (MccC7) is encoded by Escherichia coli plasmid pMccC7. However, some strains of E. coli K-12 carrying this plasmid do not produce this antibiotic. Here we show that these strains differ in the gene locus appR. This chromosomal gene product controls MccC7 production by activating the transcription of some, but not all, MccC7 plasmid genes.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
51 articles.
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