What Are the Risks—Hypothetical and Observed—of Recombination Involving Live Vaccines and Vaccine Vectors Based on Nonsegmented Negative-Strain RNA Viruses?
Author:
Affiliation:
1. National Institute of Allergy and Infectious Diseases, National Institutes of Health 50 South Drive, Room 6503 Bethesda, Maryland 20892-8007
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Link
https://journals.asm.org/doi/pdf/10.1128/JVI.01336-08
Reference20 articles.
1. Bukreyev, A., and P. L. Collins. 2008. Newcastle disease virus as a vaccine vector for humans. Curr. Opin. Mol. Ther.10:46-55.
2. Recombinant Newcastle Disease Virus Expressing a Foreign Viral Antigen Is Attenuated and Highly Immunogenic in Primates
3. Nonsegmented Negative-Strand Viruses as Vaccine Vectors
4. Chare, E. R., E. A. Gould, and E. C. Holmes. 2003. Phylogenetic analysis reveals a low rate of homologous recombination in negative-sense RNA viruses. J. Gen. Virol.84:2691-2703.
5. DiNapoli, J. M., A. Kotelkin, L. Yang, S. Elankumaran, B. R. Murphy, S. K. Samal, P. L. Collins, and A. Bukreyev. 2007. Newcastle disease virus, a host range-restricted virus, as a vaccine vector for intranasal immunization against emerging pathogens. Proc. Natl. Acad. Sci. USA104:9788-9793.
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