Targeted Amplicon Deep Sequencing for Monitoring Antimalarial Resistance Markers in Western Kenya-Reference-Cited by-同舟云学术

Targeted Amplicon Deep Sequencing for Monitoring Antimalarial Resistance Markers in Western Kenya

Published:2022-04-19 Issue:4 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Osoti Victor¹,Akinyi Mercy¹²^ORCID,Wamae Kevin¹,Kimenyi Kelvin M.¹³,de Laurent Zaydah¹,Ndwiga Leonard¹,Gichuki Paul⁴,Okoyo Collins⁴,Kepha Stella⁴,Mwandawiro Charles⁴,Kandie Regina⁵,Bejon Philip¹⁶,Snow Robert W.¹⁶,Ochola-Oyier Lynette Isabella¹^ORCID

Affiliation:

1. KEMRI-Wellcome Trust Collaborative Programme, Kilifi, Kenya

2. Institute of Primate Research, National Museums of Kenya, Nairobi, Kenya

3. Department of Biochemistry, University of Nairobi, Nairobi, Kenya

4. Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute, Nairobi, Kenya

5. Division of National Malaria Programme, Ministry of Health, Nairobi, Kenya

6. Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Abstract

Molecular surveillance of Plasmodium falciparum parasites is important to track emerging and new mutations and trends in established mutations and should serve as an early warning system for antimalarial resistance. Dried blood spots were obtained from a Plasmodium falciparum malaria survey in school children conducted across eight counties in western Kenya in 2019.

Funder

Wellcome Trust

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.01945-21

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