Ultrasensitive Detection of Clostridioides difficile Toxins A and B by Use of Automated Single-Molecule Counting Technology-Reference-Cited by-同舟云学术

Ultrasensitive Detection of Clostridioides difficile Toxins A and B by Use of Automated Single-Molecule Counting Technology

Published:2018-11 Issue:11 Volume:56 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Sandlund Johanna¹,Bartolome Amelita¹,Almazan Anna¹,Tam Stanley¹,Biscocho Sheryl¹,Abusali Salina¹,Bishop Jeffrey J.¹,Nolan Niamh¹,Estis Joel¹,Todd John¹,Young Stephen²,Senchyna Fiona³,Banaei Niaz³⁴⁵

Affiliation:

1. Singulex, Inc., Alameda, California, USA

2. TriCore Reference Laboratories, Albuquerque, New Mexico, USA

3. Department of Pathology, Stanford University School of Medicine, Stanford, California, USA

4. Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA

5. Clinical Microbiology Laboratory, Stanford Health Care, Stanford, California, USA

Abstract

Current tests for the detection of Clostridioides (formerly Clostridium ) difficile free toxins in feces lack sensitivity, while nucleic acid amplification tests lack clinical specificity. We have evaluated the Singulex Clarity C.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00908-18

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