Chromosome-Based bla OXA-48 -Like Variants in Shewanella Species Isolates from Food-Producing Animals, Fish, and the Aquatic Environment

Author:

Ceccarelli Daniela1,van Essen-Zandbergen Alieda1,Veldman Kees T.1,Tafro Nedzib2,Haenen Olga1,Mevius Dik J.13

Affiliation:

1. Wageningen Bioveterinary Research, Lelystad, The Netherlands

2. Dutch Food and Consumer Protection Authority, Utrecht, The Netherlands

3. Utrecht University, Faculty of Veterinary Medicine, Utrecht, The Netherlands

Abstract

ABSTRACT Carbapenems are considered last-resort antibiotics in health care. Increasing reports of carbapenemase-producing bacteria in food-producing animals and in the environment indicate the importance of this phenomenon in public health. Surveillance for carbapenemase genes and carbapenemase-producing bacteria in Dutch food-producing animals, environmental freshwater, and imported ornamental fish revealed several chromosome-based bla OXA-48 -like variants in Shewanella spp., including two new alleles, bla OXA-514 and bla OXA-515 . Carbapenemase genes were not associated with mobile genetic elements or Enterobacteriaceae .

Funder

Nederlandse Voedsel-en Warenautoriteit

Ministerie van Economische Zaken

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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