Increased Prevalence of Class I Integrons in Escherichia coli , Klebsiella Species, and Enterobacter Species Isolates over a 7-Year Period in a German University Hospital-Reference-Cited by-同舟云学术

Increased Prevalence of Class I Integrons in Escherichia coli , Klebsiella Species, and Enterobacter Species Isolates over a 7-Year Period in a German University Hospital

Published:2001-10 Issue:10 Volume:39 Page:3724-3726
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Schmitz Franz-Josef¹²,Hafner Dieter³,Geisel Roland¹,Follmann Patrick¹,Kirschke Christian¹,Verhoef Jan²,Köhrer Karl¹,Fluit Ad C.²

Affiliation:

1. Institute for Medical Microbiology and Virology1 and

2. Eijkman-Winkler Institute for Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands2

3. Institute of Pharmacology and Clinical Pharmacology,3 Heinrich-Heine University Düsseldorf, Düsseldorf, Germany, and

Abstract

ABSTRACT The prevalence of integrons in five enterobacterial species was analyzed in 900 blood culture isolates from 1993, 1996, and 1999. Remarkably, the prevalence increased from 4.7% in 1993 to 9.7% in 1996 and finally to 17.4% in 1999 ( P < 0.01). Within 7 years the combined percentage of P1 strong promoters and P1 weak plus P2 active promoters with high transcription efficacies has increased from 23.1 to 33.3 and finally 60% ( P < 0.05).

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.39.10.3724-3726.2001

Reference16 articles.

1. The integrons In0, In2, and In5 are defective transposon derivatives

2. New mobile gene cassettes containing an aminoglycoside resistance gene, aacA7, and a chloramphenicol resistance gene, catB3, in an integron in pBWH301

3. Expression of antibiotic resistance genes in the integrated cassettes of integrons

4. Class 1 integrons, gene cassettes, mobility, and epidemiology;Fluit A. C.;Eur. J. Clin. Microbiol. Infect. Dis.,1999

5. Site-specific insertion of genes into integrons: role of the 59-base element and determination of the recombination cross-over point;Hall R. M.;Mol. Microbiol.,1991

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