Recovery of Candida dubliniensis and Other Yeasts from Human Immunodeficiency Virus-Associated Periodontal Lesions

Author:

Jabra-Rizk M. A.1,Ferreira S. M. S.12,Sabet M.3,Falkler W. A.3,Merz W. G.4,Meiller T. F.1

Affiliation:

1. Department of Diagnostic Sciences and Pathology1 and

2. Department of Oral Diagnostic and Oral Pathology, Faculdade de Odontologia da U. F. do Rio de Janeiro, and F.O.U. Gama Filho, Rio de Janeiro, Brazil2

3. Department of OCBS,3 Dental School, University of Maryland, and

4. Department of Pathology, The Johns Hopkins University,4 Baltimore, Maryland, and

Abstract

ABSTRACT Oral and subgingival samples from periodontal lesions were collected from 54 human immunodeficiency virus (HIV)-positive and 20 HIV-negative patients and cultured for yeast species. Of the 54 samples cultured from HIV-positive patients, 44 (82%) were positive for yeast species, of which 29 (66%) were subgingival. A total of 19 (48%) patients were positive for Candida dubliniensis , of which 15 (79%) were colonized in subgingival sites. Seven isolates of Candida glabrata , two isolates of Candida parapsilosis , and one isolate of Saccharomyces cerevisiae were recovered. This study reports for the first time the recovery of C. dubliniensis from subgingival intraoral sites and confirms the presence of Candida species in sites of periodontal disease associated with HIV.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference32 articles.

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3. Periodontal problems related to HIV-1 infection;Barr C. E.;Adv. Dental Res.,1995

4. Bartlett J. Gallant J. E. Medical management of HIV infection. 2001 Johns Hopkins University School of Medicine Baltimore Md

5. Oral diseases, mycology and periodontal microbiology of HIV-1-infected women;Brady L. J.;Oral Microbiol. Immunol.,1996

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