Emerging Antimicrobial-Resistant High-Risk Klebsiella pneumoniae Clones ST307 and ST147

Author:

Peirano Gisele12,Chen Liang34ORCID,Kreiswirth Barry N.34,Pitout Johann D. D.125ORCID

Affiliation:

1. Alberta Precision Laboratories, Calgary, Alberta, Canada

2. University of Calgary, Calgary, Alberta, Canada

3. Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, USA

4. Hackensack Meridian School of Medicine at Seton Hall University, Nutley, New Jersey, USA

5. University of Pretoria, Pretoria, Gauteng, South Africa

Abstract

There is an enormous global public health burden due to antimicrobial-resistant (AMR) Klebsiella pneumoniae high-risk clones. K. pneumoniae ST307 and ST147 are recent additions to the family of successful clones in the species. Both clones likely emerged in Europe during the early to mid-1990s and, in a relatively short time, became prominent global pathogens, spreading to all continents (with the exception of Antarctica). ST307 and ST147 consist of multiple clades/clusters and are associated with various carbapenemases (i.

Funder

HHS | National Institutes of Health

Canadian Institutes of Health Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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