Comparison of Midturbinate Flocked-Swab Specimens with Nasopharyngeal Aspirates for Detection of Respiratory Viruses in Children by the Direct Fluorescent Antibody Technique

Author:

Faden Howard1

Affiliation:

1. Department of Pediatrics, Division of Infectious Diseases, State University of New York at Buffalo School of Medicine and Biomedical Sciences, and the Women and Children's Hospital of Buffalo, New York

Abstract

ABSTRACT Paired nasopharyngeal aspirate (NPA) and midturbinate flocked-swab specimens from 153 children with respiratory symptoms were examined by the direct fluorescent antibody (DFA) technique. Seventy-four infants (49%) had a viral infection documented by DFA. The flocked-swab specimens had 93% sensitivity and 96.7% agreement with the NPA specimens, with a kappa coefficient of 93.4% (95% confidence interval, 0.877, 0.991).

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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