Comparison of Two Commercial Molecular Assays to a Laboratory-Developed Molecular Assay for Diagnosis of Clostridium difficile Infection

Author:

Karre Tess1,Sloan Lynne1,Patel Robin12,Mandrekar Jayawant3,Rosenblatt Jon12

Affiliation:

1. Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology

2. Division of Infectious Diseases, Department of Medicine

3. Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota

Abstract

ABSTRACT We compared two commercial PCR assays, the Prodesse ProGastro CD assay and the BD GeneOhm Cdiff assay, with a laboratory-developed Clostridium difficile toxin PCR assay with previously established performance characteristics. Results of all methods were in agreement for 333 (96%) of 346 stool specimens. No significant difference in performance among the assays was found ( P values, >0.05).

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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