Differential Splicing of Human Adenovirus 5 E1A RNA Expressed in cis versus in trans-Reference-Cited by-同舟云学术

Differential Splicing of Human Adenovirus 5 E1A RNA Expressed in cis versus in trans

Published:2021-02-24 Issue:6 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Graves Drayson¹,Akkerman Nikolas¹,Bachus Scott¹,Pelka Peter¹²^ORCID

Affiliation:

1. Department of Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada

2. Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada

Abstract

Human adenovirus has become an important tool for medicine and research, and 293 cells and various similar cell lines are used extensively for virus production in situations where high viral yields are important. Such complementing cell lines are used for the production of viral vectors and vaccines, which often have deletions and replacements in various viral genes.

Funder

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Gouvernement du Canada | Canadian Institutes of Health Research

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.02081-20

Reference37 articles.

1. An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA

2. Spliced segments at the 5′ terminus of adenovirus 2 late mRNA

3. Drosophila Dscam Is an Axon Guidance Receptor Exhibiting Extraordinary Molecular Diversity

4. Knipe DM, Howley PM, Cohen JI, Griffin DE, Lamb RA, Martin MA, Racaniello VR, Roizman B (ed). 2013. Fields virology, 6th ed. Wolters Kluwer/Lippincott Williams & Wilkins Health, Philadelphia, PA.

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. HBO1/KAT7/MYST2 HAT complex regulates human adenovirus replicative cycle;Heliyon;2024-04

2. ARGLU1 enhances promoter-proximal pausing of RNA polymerase II and stimulates DNA damage repair;Nucleic Acids Research;2024-03-23

3. Circulating exosome-mediated AMPKα–SIRT1 pathway regulates lipid metabolism disorders in calf hepatocytes;Research in Veterinary Science;2024-03

4. Engineered Human Adenoviruses of Species B and C Report Early, Intermediate Early, and Late Viral Gene Expression;Human Gene Therapy;2023-12-01

5. Adenovirus Transcriptome in Human Cells Infected with ChAdOx1-Vectored Candidate HIV-1 Vaccine Is Dominated by High Levels of Correctly Spliced HIVconsv1&62 Transgene RNA;Vaccines;2023-07-01