Detection of (1→3)-β- d -Glucan as an Adjunct to Diagnosis in a Mixed Population with Uncommon Proven Invasive Fungal Diseases or with an Unusual Clinical Presentation

Author:

Cuétara María Soledad1234,Alhambra Almudena1234,Moragues María Dolores1234,González-Elorza Ernesto1234,Pontón José1234,del Palacio Amalia1234

Affiliation:

1. Servicio de Microbiología, Hospital Severo Ochoa, Leganés, Madrid

2. Unidad de Micología, Departamento de Microbiología, Hospital Universitario 12 de Octubre, Madrid

3. Departamento de Enfermería I, Universidad del País Vasco, Lejona, Vizcaya

4. Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco, Lejona, Vizcaya, Spain

Abstract

ABSTRACT This single-center observational prospective study evaluated the performance of (1→3)-β- d -glucan as an adjunct diagnostic tool in 12 patients with proven invasive fungal disease with different risk factors. The infections were due to either uncommon fungal pathogens such as dematiaceous molds ( Scedosporium apiospermum , Alternaria infectoria , and Cladosporium macrocarpum ) and hyaline septate molds ( Fusarium solani and Blastoschizomyces capitatus ) or Aspergillus spp. with unusual clinical presentations.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

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