Protein Splicing of SufB Is Crucial for the Functionality of the Mycobacterium tuberculosis SUF Machinery-Reference-Cited by-同舟云学术

Protein Splicing of SufB Is Crucial for the Functionality of the Mycobacterium tuberculosis SUF Machinery

Published:2006-05 Issue:9 Volume:188 Page:3412-3414
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Huet Gaëlle¹,Castaing Jean-Philippe¹,Fournier Didier¹,Daffé Mamadou¹,Saves Isabelle¹

Affiliation:

1. Department of Molecular Mechanisms of Mycobacterial Infections, Institut de Pharmacologie et Biologie Structurale (UMR5089), CNRS/Université Paul Sabatier Toulouse III, 205 Route de Narbonne, F-31077 Toulouse Cedex, France

Abstract

ABSTRACT The SufBCD complex is an essential component of the SUF machinery of [Fe-S] cluster biogenesis in many organisms. We show here that in Mycobacterium tuberculosis the formation of this complex is dependent on the protein splicing of SufB, suggesting that this process is a potential new target for antituberculous drugs.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.188.9.3412-3414.2006

Reference18 articles.

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5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

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