Inhibition of growth of Chlamydia trachomatis by human gamma interferon-Reference-Cited by-同舟云学术

Inhibition of growth of Chlamydia trachomatis by human gamma interferon

Published:1985-05 Issue:2 Volume:48 Page:592-596
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Shemer Y,Sarov I

Abstract

Treatment of HEp-2 cell cultures with highly purified human gamma interferon before infection resulted in the reduction of Chlamydia trachomatis (L2/434/Bu) infectious particle yield. Electron microscope studies showed that interferon did not affect chlamydial conversion to reticulate bodies but influenced the extent of maturation to elementary bodies. High interferon concentrations (greater than 350 IU/ml) inhibited inclusion body formation and resulted in the appearance of aberrant reticulate bodies.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.48.2.592-596.1985

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