Adjuvant effects of diethylaminoethyl-dextran

Author:

Houston W E,Crabbs C L,Kremer R J,Springer J W

Abstract

Diethylaminoethyl-dextran exhibited a significant effect on the primary immune response of rhesus monkeys to formalin-inactivated Venezuelan equine encephalomyelitis virus vaccine (IVEE). Antibody formed to IVEE and adjuvant followed a classic immunoglobulin M-immunoglobulin G pattern; however, as compared with vaccine alone, use of this adjuvant with IVEE reduced the time required for onset of immunoglobulin G synthesis.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference17 articles.

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3. In vivo enhancement of rabies infection by diethylaminoethyl-dextran;Bijlenga G.;Arch. Gesamte Virusforsch.,1973

4. Inactivated Venezuelan equine encephalomyelitis vaccine prepared from attenuated (TC-83 strain) virus;Cole F. E.;Appl. Microbiol.,1974

5. A two-stage model for development of antibody-producing cells;Cooper M. D.;Clin. Exp. Immunol.,1972

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