Mac1-Dependent Copper Sensing Promotes <i>Histoplasma</i> Adaptation to the Phagosome during Adaptive Immunity-Reference-Cited by-同舟云学术

Mac1-Dependent Copper Sensing Promotes Histoplasma Adaptation to the Phagosome during Adaptive Immunity

Published:2022-04-26 Issue:2 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Ray Stephanie C.¹^ORCID,Rappleye Chad A.¹^ORCID

Affiliation:

1. Department of Microbiology, Ohio State University, Columbus, Ohio, USA

Abstract

Histoplasma capsulatum is a fungal pathogen that survives and grows within host macrophages. For successful infection, Histoplasma must sense and adapt to a dynamic intracellular environment over the course of an infection.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.03773-21

Reference41 articles.

1. Nutritional immunity: transition metals at the pathogen–host interface

2. The Yin and Yang of copper during infection

3. Histoplasma capsulatum pathogenesis: making a lifestyle switch

4. Histoplasma yeast and mycelial transcriptomes reveal pathogenic-phase and lineage-specific gene expression profiles

5. RNA interference in Histoplasma capsulatum demonstrates a role for α-(1,3)-glucan in virulence

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