Cryptococcus neoformans Galactoxylomannan Contains an Epitope(s) That Is Cross-Reactive with Aspergillus Galactomannan-Reference-Cited by-同舟云学术

Cryptococcus neoformans Galactoxylomannan Contains an Epitope(s) That Is Cross-Reactive with Aspergillus Galactomannan

Published:2005-06 Issue:6 Volume:43 Page:2929-2931
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Dalle Frédéric¹,Charles Pierre Emmanuel²,Blanc Karine¹,Caillot Denis³,Chavanet Pascal²,Dromer Françoise⁴,Bonnin Alain¹

Affiliation:

1. Laboratoire de Parasitologie Mycologie, CHU, Hôpital du Bocage, and Laboratoire de Microbiologie Médicale et Moléculaire, Faculté de Médecine, Dijon, France

2. Service des Maladies Infectieuses et Tropicales, CHU, Hôpital d'enfants, and Laboratoire de Microbiologie Médicale et Moléculaire, Faculté de Médecine, Dijon, France

3. Service d'Hématologie Clinique, CHU, Hôpital d'enfants, Dijon, France

4. Centre National de Référence de la Mycologie et des Antifongiques, Institut Pasteur, Paris, France

Abstract

ABSTRACT We report a case of cryptococcosis in which a serum enzyme-linked immunosorbent assay (ELISA) for Aspergillus galactomannan was positive, with no evidence of aspergillosis. Soluble antigens from 19 Cryptococcus neoformans strains and purified carbohydrates of C. neoformans capsule were thus assayed in the Aspergillus galactomannan ELISA. Antigens from all C. neoformans strains, and purified galactoxylomannan, gave a positive reaction, suggesting that C. neoformans galactoxylomannan contains an epitope(s) that is cross-reactive with Aspergillus galactomannan.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.43.6.2929-2931.2005

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