Author:
Sharma A,Haq A,Ahmad S,Lederer E
Abstract
Rabbits were immunized with soluble Entamoeba histolytica antigen with an aqueous suspension of trehalose-6,6'-dimycolate used as the adjuvant. Induction of protective immunity in the immunized animals was demonstrated by enhanced humoral and cell-mediated immune responses and 100% survival after challenge. Administration of soluble antigen only failed to induce a similar degree of protective immunity. Trehalose-6,6'-dimycolate alone produced only a slight increase in nonspecific resistance.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
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