Bacteriophage Resistance Affects Flavobacterium columnare Virulence Partly via Mutations in Genes Related to Gliding Motility and the Type IX Secretion System

Author:

Kunttu Heidi M. T.1,Runtuvuori-Salmela Anniina1,Sundell Krister2,Wiklund Tom2,Middelboe Mathias3ORCID,Landor Lotta2,Ashrafi Roghaieh1,Hoikkala Ville1ORCID,Sundberg Lotta-Riina1ORCID

Affiliation:

1. Department of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, Jyväskylä, Finland

2. Laboratory of Aquatic Pathobiology, Åbo Akademi University, Turku, Finland

3. Department of Biology, Marine Biological Section, University of Copenhagen, Helsingør, Denmark

Abstract

Phage resistance of infectious bacteria is a common phenomenon posing challenges for the development of phage therapy. Along with a growing world population and the need for increased food production, constantly intensifying animal farming has to face increasing problems of infectious diseases.

Funder

BONUS

Jane and Aatos Erkko foundation

Academy of Finland

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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