Penicillins Activate Autolysins Extracted from Both Escherichia coli and Klebsiella pneumoniae Envelopes-Reference-Cited by-同舟云学术

Penicillins Activate Autolysins Extracted from Both Escherichia coli and Klebsiella pneumoniae Envelopes

Published:1977-12 Issue:6 Volume:12 Page:745-747
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Fontana Roberta¹,Satta G.¹,Romanzi C. A.¹

Affiliation:

1. Institute of Microbiology, University of Genoa, Genoa, Italy 16132

Abstract

Ampicillin at a 50-μg/ml concentration effects a doubling of the autolysis rate of cell envelopes isolated from Klebsiella pneumoniae Mir A12. This antibiotic increases also by two- to threefold the depolymerizing activity of both K. pneumoniae and Escherichia coli crude extracts on a labeled peptidoglycan-lipoprotein complex. Several other penicillins also activate autolysins.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.12.6.745

Reference1 articles.

1. Interaction of pencillin with the bacterial cells: penicillinbinding proteins and pencillin-sensitive enzymes;Ilumberg P. M.;Bacteriol. Rev.,1974

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