Vi Antigen from Salmonella typhosa and Immunity Against Typhoid Fever I. Isolation and Immunologic Properties in Animals-Reference-Cited by-同舟云学术

Vi Antigen from Salmonella typhosa and Immunity Against Typhoid Fever I. Isolation and Immunologic Properties in Animals

Published:1974-02 Issue:2 Volume:9 Page:348-353
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Wong K. H.¹²,Feeley John C.¹²,Northrup R. S.¹²,Forlines M. E.¹²

Affiliation:

1. Division of Bacterial Products, Bureau of Biologics, Food and Drug Administration, Rockville, Maryland 20852

2. Bacteriology Branch, Center for Disease Control, Atlanta, Georgia 30333

Abstract

The role of Vi antigen in human immunity against typhoid fever has been debated for decades. Circumstantial evidence indicates that Vi antigen may play a role in pathogenicity and immunity. A Vi preparation was isolated from Salmonella typhosa , the causative organism in human typhoid fever, by a mild precipitation method. It was significantly more potent in animal studies than preparations from Citrobacter used in the past for human study and less toxic than conventional typhoid vaccines. With this antigen, the role of Vi antigen in human protection is now being investigated.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.9.2.348-353.1974

Reference24 articles.

1. The VI antigens of the Enterobacteriaceae. I. Purification and chemical properties;Baker E. E.;J. Immunol.,1959

2. Serological responses of man to typhoid vaccines;Bennenson A. S.;Bull. W. H. O.,1964

3. Application of the logistic function to bioassay;Berkson J.;J. Amer. Statist. Ass.,1944

4. Bliss C. I. and C. White. 1967. Statistical methods in biological assay of the vitamins p. 21-137. In P. Gyoirgy and W. N. Pearson (ed. The vitamins: chem

5. The present status of field and laboratory studies of typhoid and paratyphoid vaccines: with special reference to studies sponsored by the World Health;Cvjetanovic B.;Organization. Bull. W. H. O.,1965

Cited by 48 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Typhoid Fever Vaccines;Plotkin's Vaccines;2023

2. A Short History of Vaccination;Plotkin's Vaccines;2023

3. Typhoid vaccines. Historical aspects of typhoid vaccine development, and currently available products;BIOpreparations. Prevention, Diagnosis, Treatment;2021-07-01

4. Vaccine Development Against Salmonella Typhi: A Search is Still On;JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH;2019

5. Typhoid Fever Vaccines;Plotkin's Vaccines;2018