Serum antibodies in Campylobacter enteritis

Author:

Kaldor J,Pritchard H,Serpell A,Metcalf W

Abstract

A solid-phase enzyme immunoassay method for the measurement of total and class-specific serum antibodies to Campylobacter jejuni was developed. The test was found to be both sensitive and specific. Immunoglobulin M, G, and A antibodies were detected in about 90% of sera collected from patients recovering from Campylobacter enteritis, with the pattern of appearance and decline of these antibodies conforming to that usually seen in an acute infection. A poor antibody response was noted in patients with intermittent or prolonged enteritis. The clinical implications and diagnostic value of this test are discussed.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference18 articles.

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