Evaluation of a latex agglutination test for detection of antibodies to rubella virus in selected sera

Author:

Freeman S,Clark L,Dumas N

Abstract

A new latex agglutination test for rubella virus was used to test sera with a hemagglutination inhibition titer of less than or equal to 8 (97 specimens) or greater than or equal to 256 (158 specimens). Maximum latex agglutination test sensitivity was achieved when low-titer sera were tested undiluted and high-titer sera were diluted (1:10). A modification of the protocol of the manufacturer resulted in a latex agglutination-hemagglutination inhibition agreement of 96.7%.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference8 articles.

1. Evaluation of commercially available diagnostic test kits for rubella;Castellano G. A.;J. Infect. Dis.,1981

2. Delbel R. 1982. Rubella serology: a technical overview p. 2-6. In K. Wicher R. W. Stevens and K. E. Hechemy (ed.) Infectious Disease Institute newsletter. New York State Department of Health Albany.

3. Solid-phase radioimmunoassay of rubella virus immunoglobulin G and immunoglobulin M antibodies;Kalimo K.;J. Clin. Microbiol.,1976

4. Comparison of the latex agglutination test with the hemagglutination inhibition test, enzyme-linked immunosorbent assay, and neutralization test for detection of antibodies to rubella virus;Meegan J. M.;J. Clin. Microbiol.,1982

5. A comparison of three tests for rubella antibody screening;Morgan-Capner P.;J. Clin. Pathol.,1979

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