Characterizing the Pathogenic Potential of Crohn’s Disease-Associated Adherent-Invasive Escherichia coli

Abstract

The microbiome of Crohn’s disease (CD) patients is composed of a microbial community that is considered dysbiotic and proinflammatory in nature. The overrepresentation of Enterobacteriaceae species is a common feature of the CD microbiome, and much attention has been given to understanding the pathogenic role this feature plays in disease activity.