ShmR Is Essential for Utilization of Heme as a Nutritional Iron Source in Sinorhizobium meliloti-Reference-Cited by-同舟云学术

ShmR Is Essential for Utilization of Heme as a Nutritional Iron Source in Sinorhizobium meliloti

Published:2008-10-15 Issue:20 Volume:74 Page:6473-6475
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Amarelle Vanesa¹,O'Brian Mark R.²,Fabiano Elena¹

Affiliation:

1. Laboratorio de Ecología Microbiana, Instituto de Investigaciones Biológicas Clemente Estable, MEC, Unidad Asociada a la Facultad de Ciencias, Av. Italia 3318, Montevideo 11600, Uruguay

2. Department of Biochemistry, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York 14214

Abstract

ABSTRACT The bacterium Sinorhizobium meliloti is able to use heme as a nutritional iron source. Here, we show that the iron-regulated shmR gene encodes an outer membrane protein required for growth on heme. Furthermore, an shmR mutant is resistant to the toxic heme analog gallium protoporphyrin. Thus, the receptor protein of the heme transport system has been identified in S. meliloti .

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.01590-08

Reference14 articles.

1. Allaway, D., N. A. Schofield, M. E. Leonard, L. Gilardoni, T. M. Finan, and P. S. Poole. 2001. Use of differential fluorescence induction and optical trapping to isolate environmentally induced genes. Environ. Microbiol.3:397-406.

2. Identification of an Iron-Regulated, Hemin-Binding Outer Membrane Protein in Sinorhizobium meliloti

3. Becker, A., M. Schmidt, W. Jager, and A. Puhler. 1995. New gentamicin-resistance and lacZ promoter-probe cassettes suitable for insertion mutagenesis and generation of transcriptional fusions. Gene162:37-39.

4. Beringer, J. E. 1974. R factor transfer in Rhizobium leguminosarum.J. Gen. Microbiol.84:188-198.

5. Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans

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