Lower Density and Shorter Duration of Nasopharyngeal Carriage by Pneumococcal Serotype 1 (ST217) May Explain Its Increased Invasiveness over Other Serotypes-Reference-Cited by-同舟云学术

Lower Density and Shorter Duration of Nasopharyngeal Carriage by Pneumococcal Serotype 1 (ST217) May Explain Its Increased Invasiveness over Other Serotypes

Published:2020-12-22 Issue:6 Volume:11 Page:
ISSN:2161-2129
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Bricio-Moreno Laura¹^ORCID,Chaguza Chrispin¹²,Yahya Reham¹,Shears Rebecca K.¹,Cornick Jennifer E.¹²,Hokamp Karsten³,Yang Marie¹,Neill Daniel R.¹,French Neil¹,Hinton Jay C. D.⁴,Everett Dean B.¹²,Kadioglu Aras¹^ORCID

Affiliation:

1. Institute of Infection and Global Health, Department of Clinical Infection, Microbiology, and Immunology, University of Liverpool, Liverpool, United Kingdom

2. Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi, College of Medicine, Blantyre, Malawi

3. Department of Genetics, School of Genetics and Microbiology, Smurfit Institute of Genetics, Trinity College, Dublin, Ireland

4. Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom

Abstract

The pneumococcus causes serious diseases such as pneumonia, sepsis, and meningitis and is a major cause of morbidity and mortality worldwide. Serotype 1 accounts for the majority of invasive pneumococcal disease cases in sub-Saharan Africa but is rarely found during nasopharyngeal carriage.

Funder

PhD studentship

Saudi Cultural Bureau

UKRI | Medical Research Council

Bill and Melinda Gates Foundation

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00814-20

Reference80 articles.

1. Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates

2. Prevention of pneumococcal disease: recommendations of the Advisory Committee on Immunization Practices (ACIP);Advisory Committee on Immunization Practices;MMWR Morb Mortal Wkly Rep,1997

3. Genetic Analysis of the Capsular Biosynthetic Locus from All 90 Pneumococcal Serotypes

4. Capsule Type of Streptococcus pneumoniae Determines Growth Phenotype

5. Genetic Alteration of Capsule Type but Not PspA Type Affects Accessibility of Surface-Bound Complement and Surface Antigens of Streptococcus pneumoniae

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