Increased Production of Outer Membrane Vesicles by Salmonella Interferes with Complement-Mediated Innate Immune Attack-Reference-Cited by-同舟云学术

Increased Production of Outer Membrane Vesicles by Salmonella Interferes with Complement-Mediated Innate Immune Attack

Published:2021-06-29 Issue:3 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Dehinwal Ruchika¹,Cooley Danielle¹,Rakov Alexey V.¹,Alugupalli Akhil S.¹,Harmon Joey²,Cunrath Olivier³,Vallabhajosyula Prashanth²,Bumann Dirk³,Schifferli Dieter M.¹^ORCID

Affiliation:

1. Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, Pennsylvania, USA

2. Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA

3. Biozentrum, University of Basel, Basel, Switzerland

Abstract

Bacterial outer membrane vesicles (OMVs) mediate critical bacterium-bacterium and host-microbial interactions that influence pathogenesis through multiple mechanisms, including the elicitation of inflammatory responses, delivery of virulence factors, and enhancement of biofilm formation. As such, there is a growing interest in understanding the underlying mechanisms of OMV production.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00869-21

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