PKR Binds Enterovirus IRESs, Displaces Host Translation Factors, and Impairs Viral Translation to Enable Innate Antiviral Signaling-Reference-Cited by-同舟云学术

PKR Binds Enterovirus IRESs, Displaces Host Translation Factors, and Impairs Viral Translation to Enable Innate Antiviral Signaling

Published:2022-06-28 Issue:3 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Dobrikov Mikhail I.¹,Dobrikova Elena Y.¹,McKay Zachary P.¹,Kastan Jonathan P.¹^ORCID,Brown Michael C.¹,Gromeier Matthias¹^ORCID

Affiliation:

1. Department of Neurosurgery, Duke University Medical School, Durham, North Carolina, USA

Abstract

Among the RIG-I-like pattern recognition receptors, MDA5 stands out because it senses long dsRNA duplexes independent of their 5′ features (RIG-I recognizes viral [v]RNA 5′-ppp blunt ends).

Funder

HHS | NIH | National Institute of Neurological Disorders and Stroke

HHS | NIH | National Cancer Institute

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00854-22

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