EGR1 Suppresses Porcine Epidemic Diarrhea Virus Replication by Regulating IRAV To Degrade Viral Nucleocapsid Protein

Author:

Wang Hua1,Kong Ning12,Jiao Yajuan1,Dong Sujie1,Sun Dage1,Chen Xiaoyong1,Zheng Hao12,Tong Wu12,Yu Hai12,Yu Lingxue12,Zhang Wen3,Tong Guangzhi12,Shan Tongling12ORCID

Affiliation:

1. Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, People’s Republic of China

2. Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, People’s Republic of China

3. School of Medicine, Jiangsu University, Zhenjiang, People’s Republic of China

Abstract

PEDV is a highly contagious enteric coronavirus that has rapidly emerged worldwide and has caused severe economic losses. No currently available drugs or vaccines can effectively control PEDV.

Funder

National Key Research and Development Programs of China

Natural Science Foundation of Shanghai

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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