Author:
Gibbs R S,Blanco J D,Castaneda Y S,St Clair P J
Abstract
We evaluated moxalactam in 62 patients with puerperal or postabortal genital infections. In all patients, the initial dose was 6 g/day. In 84% of patients, we found anaerobes in genital specimens. Of aerobic isolates, only enterococci were resistant. Among anaerobes tested, only two isolates (a Clostridium leptum and a Bacteroides disiens) had minimal inhibitory concentrations of greater than or equal to microgram/ml. Good clinical responses occurred in 56 of 62 (90%). Moxalactam was well tolerated with little local irritation and minimal hepatic, renal, or hematological abnormalities.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference13 articles.
1. In vitro activity of LY127935;Barza M.;Antniicrob. Agents Chemother.,1979
2. Treatment of obstetric and gynecologic infections with cefamandole;Cunningham F. G.;Am. J. Obstet. Gynecol.,1979
3. In vitro activity of LY127935;Faso R. J.;Antimicrob. Agents Chemother.,1979
4. Cefamandole therapy of endomyometritis following cesarean section;Gibbs R. S.;Am. J. Obstet. Gynecol.,1980
5. Antibiotic therapy of endometritis following cesarean section, treatment success and failures;Gibbs R. S.;Obstet. Gynecol.,1978
Cited by
34 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献