Exploring the Ecological Effects of Naturally Antibiotic-Insensitive Bifidobacteria in the Recovery of the Resilience of the Gut Microbiota during and after Antibiotic Treatment

Author:

Argentini Chiara1,Mancabelli Leonardo1,Alessandri Giulia1,Tarracchini Chiara1,Barbetti Margherita23,Carnevali Luca24,Longhi Giulia15,Viappiani Alice5,Anzalone Rosaria5,Milani Christian14ORCID,Sgoifo Andrea24,van Sinderen Douwe6ORCID,Ventura Marco14ORCID,Turroni Francesca14ORCID

Affiliation:

1. Laboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy

2. Stress Physiology Laboratory, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy

3. Department of Medicine and Surgery, University of Parma, Parma, Italy

4. Interdepartmental Research Centre Microbiome Research Hub, University of Parma, Parma, Italy

5. GenProbio srl, Parma, Italy

6. APC Microbiome Institute and School of Microbiology, Bioscience Institute, National University of Ireland, Cork, Ireland

Abstract

The first microbial colonizers of the infant gut are members of the genus Bifidobacterium , which exhibit different activities beneficial to their host. Amoxicillin-clavulanic acid (AMC) is the most frequently prescribed antibiotic during infancy, and few strains of bifidobacteria are known to show a natural resistance to this antibiotic.

Funder

Programma operativo nazionale ricerca e innovazione

Ministero della Salute

UCC | APC Microbiome Institute

Fondazione Cariparma

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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