Epidemiology and Transmission of Carbapenemase-Producing Enterobacteriaceae in a Health Care Network of an Acute-Care Hospital and Its Affiliated Intermediate- and Long-Term-Care Facilities in Singapore

Author:

Aung Aung-Hein1ORCID,Kanagasabai Kala2,Koh Jocelyn3,Hon Pei-Yun1,Ang Brenda45,Lye David456,Chen Swaine L.67ORCID,Chow Angela15ORCID

Affiliation:

1. Department of Clinical Epidemiology, Office of Clinical Epidemiology, Analytics, and Knowledge, Tan Tock Seng Hospital, Singapore, Singapore

2. Ren Ci Hospital, Singapore, Singapore

3. Ang Mo Kio—Thye Hua Kwan Hospital, Singapore, Singapore

4. Department of Infectious Disease, Tan Tock Seng Hospital, Singapore, Singapore

5. Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore

6. Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

7. Laboratory of Bacterial Genomics, Genome Institute of Singapore, A*STAR, Singapore, Singapore

Abstract

Movement of patients in a health care network poses challenges for the control of carbapenemase-producing Enterobacteriaceae (CPE). We aimed to identify intra- and interfacility transmission events and facility type-specific risk factors of CPE in an acute-care hospital (ACH) and its intermediate-term and long-term-care facilities (ILTCFs).

Funder

Agency for Science, Technology and Research

Ministry of Health -Singapore

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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