Vancomycin Susceptibility of Oxacillin-Resistant Staphylococcus aureus Isolates Causing Nosocomial Bloodstream Infections

Author:

Tallent Sandra M.1,Bischoff Tammy1,Climo Michael12,Ostrowsky Belinda1,Wenzel Richard P.1,Edmond Michael B.1

Affiliation:

1. Department of Internal Medicine, Medical College of Virginia Campus of Virginia Commonwealth University

2. Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Virginia

Abstract

ABSTRACT Nosocomial oxacillin-resistant Staphylococcus aureus (ORSA) bloodstream isolates were tested to determine the prevalence of vancomycin heteroresistance. We screened 619 ORSA nosocomial bloodstream isolates from 36 hospitals between 1997 and 2000. Only one isolate exhibiting heterotypic resistance was detected. Thus, vancomycin heteroresistance in clinical bloodstream isolates remains rare in the United States.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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