Enterococcus faecalis Maltodextrin Gene Regulation by Combined Action of Maltose Gene Regulator MalR and Pleiotropic Regulator CcpA

Author:

Grand Maxime1ORCID,Riboulet-Bisson Eliette1ORCID,Deutscher Josef23,Hartke Axel1ORCID,Sauvageot Nicolas1ORCID

Affiliation:

1. Normandie University, UNICAEN, U2RM Stress/Virulence, Caen, France

2. Micalis Institute, INRAE, AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France

3. UMR 8261, CNRS, Université de Paris, Institut de Biologie Physico-Chimique, Paris, France

Abstract

Enterococcus faecalis represents a leading cause of hospital-acquired infections worldwide. Several studies highlighted the importance of carbohydrate metabolism in the infection process of this bacterium. The genes required for maltodextrin metabolism are particularly induced during mouse infection and, therefore, should play an important role for pathogenesis. Since no data were hitherto available concerning the regulation of expression of the maltodextrin operons, we have conducted experiments to study the underlying mechanisms.

Funder

Ministère de l'Enseignement supérieur, de la Recherche et de l'Innovation

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference52 articles.

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